The Federal Water Pollution Control Act (now commonly referred to as the Clean Water Act) was originally adopted in 1948. Amendments to this Act in 1965 for the first time required states to adopt water quality criteria for interstate waters and a plan for implementation and enforcement of the criteria.
EPA - My Environment
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EPA - Laws & Regulations
EPA is called a regulatory agency because congress authorizes us to write regulations that explain the technical, operational, and legal details necessary to implement laws. Regulations are mandatory requirements that can apply to individuals, businesses, state or local governments, non-profit institutions, or others.